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Research

The Department of Pathology is deeply invested in scientific efforts to improve treatments in our field. Learn more about our department’s investigations below.

Message from the Vice Chair

"We are driven by a shared passion for discovery and a deep commitment to advancing human health through innovative research programs and collaborative partnerships among scientists and pathologists."

Peng Ji, MD, PhD
Vice Chair of Research 

Read Full Message

Areas of Research

Members of the Department of Pathology are defining the cellular and molecular basis of disease toward the development of new and improved strategies to diagnose and treat, inherited, acquired and infectious disorders. Learn more about the work being done in our labs.

Research Areas

Affiliated Research Centers and Institutes

The faculty members of Northwestern University Feinberg School of Medicine’s Department of Pathology are engaged in research within the department and throughout Northwestern Medicine and Northwestern University. Our work throughout the community, including director appointments, illustrate the importance we put on scientific collaboration.

Research Cores

Core facilities provide cost-efficient access of state-of-the-art equipment, the most current technologies and expert technical advice to individual scientists.

Learn more about our affiliated cores

Research Resources

Recent Publications

Adaptation and changing phenotypes through transgenerational epigenetics.

Van Winkle LJ, Ryznar RJ, Iannaccone PM.

Epigenetics. 2025 Dec;20(1):2460246. doi: 10.1080/15592294.2025.2460246. Epub 2025 Aug 13.

Life-course socioeconomic position and the gut microbiome in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).

Batalha MA, LeCroy MN, Lin J, Peters BA, Qi Q, Wang Z, Wang T, Gallo LC, Talavera GA, McClain AC, Thyagarajan B, Daviglus ML, Hou L, Llabre M, Cai J, Kaplan RC, Isasi CR.

Gut Microbes. 2025 Dec;17(1):2479772. doi: 10.1080/19490976.2025.2479772. Epub 2025 Mar 18.

Efficacy of benznidazole delivery during Chagas disease nanotherapy is dependent on the nanocarrier morphology.

Scariot DB, Staneviciute A, Machado RRB, Yuk SA, Liu YG, Sharma S, Almunif S, Arona Mbaye EH, Nakamura CV, Engman DM, Scott EA.

Biomaterials. 2025 Nov;322:123358. doi: 10.1016/j.biomaterials.2025.123358. Epub 2025 Apr 22.

Carboplatin, gemcitabine, and mifepristone for advanced breast and recurrent/persistent epithelial ovarian cancer.

Stringer-Reasor EM, Saha P, Kocherginsky M, Lastra R, Baker G, Lenygel E, Karrison T, Olalde L, Mokrzycki E, Hahn OM, Hoffman PC, Conzen SD, Fleming GF, Nanda R.

Breast Cancer Res Treat. 2025 Oct;213(3):347-354. doi: 10.1007/s10549-025-07783-7. Epub 2025 Aug 8.

DNA methylation biomarkers for cervical cancer risk prediction in HIV-positive Nigerian women.

Zheng Y, Han J, Qu Y, Wang J, Joyce BT, Kim K, Nannini DR, Musa J, Imade GE, Anorlu R, Maiga M, Morhason-Bello I, Simon MA, Silas O, Abdulkareem FB, Badmos K, Nyam CJ, Gursel DB, Wei JJ, Novo J, Sulaimon AA, Kayat LS, Kocherginsky M, Kim KA, Burdett K, Katam N, Achenbach CJ, Sagay AS, Ogunsola FT, Murphy RL, Hou L.

Int J Cancer. 2025 Oct 1;157(7):1363-1375. doi: 10.1002/ijc.35502. Epub 2025 Jun 9.

UTERINE FIBROIDS.

Bulun SE, Yin P, Wei J, Zuberi A, Iizuka T, Suzuki T, Saini P, Goad J, Parker JB, Adli M, Boyer T, Chakravarti D, Rajkovic A.

Physiol Rev. 2025 Oct 1;105(4):1947-1988. doi: 10.1152/physrev.00010.2024. Epub 2025 Apr 11.

Outcomes After Acute Plasma Exchange for Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease.

Thakolwiboon S, Redenbaugh V, Chen B, Hewitt S, Shah S, Lotan I, Levy M, Forcadela M, Huda S, Pique J, Marignier R, Boutiere C, Audoin B, Poullin P, Champsas D, Choi D, Danesh-Meyer HV, Vasileiou E, Sotirchos ES, Davis JB, Henderson AD, Wilf-Yarkoni A, Stiebel-Kalish H, Maillart E, Bonelli L, Arnold AC, Boudot De La Motte M, Deschamps R, Jitprapaikulsan J, Moss HE, Villarreal Navarro SE, Mao-Draayer Y, Mishra M, Vorasoot N, Cacciaguerra L, Tisavipat N, Tajfirouz DA, Tillema JM, Lopez-Chiriboga SA, Palace J, Hacohen Y, Pittock SJ, Flanagan EP, Chen JJ.

Neurology. 2025 Sep 23;105(6):e213903. doi: 10.1212/WNL.0000000000213903. Epub 2025 Aug 29.

Antifungal spectrum of cyclobutrifluram and multi-point mutations in CcSdh proteins confer resistance in Corynespora cassiicola.

Hao X, Li Y, Hang Z, Chen Y, Tang Y, Miao J, Peng Q, Liu X.

Stress Biol. 2025 Sep 1;5(1):53. doi: 10.1007/s44154-025-00251-8.

Regional lymph node invasion in pediatric non-rhabdomyosarcoma soft tissue sarcoma: an international cohort study from the International Soft Tissue Sarcoma Consortium.

Orbach D, Carton M, Heinz AT, Borgwardt L, Brisse JH, Morosi C, Rudzinski ER, Safwat A, Sparber-Sauer M, Terezakis S, Ferrari A, Weiss AR, Meyer WH, Walterhouse DO, Lautz TB.

EClinicalMedicine. 2025 Aug 7;87:103409. doi: 10.1016/j.eclinm.2025.103409. eCollection 2025 Sep.

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