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Research

The Department of Pathology is deeply invested in scientific efforts to improve treatments in our field. Learn more about our department’s investigations below.

Message from the Vice Chair

"We are driven by a shared passion for discovery and a deep commitment to advancing human health through innovative research programs and collaborative partnerships among scientists and pathologists."

Peng Ji, MD, PhD
Vice Chair of Research 

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Areas of Research

Members of the Department of Pathology are defining the cellular and molecular basis of disease toward the development of new and improved strategies to diagnose and treat, inherited, acquired and infectious disorders. Learn more about the work being done in our labs.

Research Areas

Affiliated Research Centers and Institutes

The faculty members of Northwestern University Feinberg School of Medicine’s Department of Pathology are engaged in research within the department and throughout Northwestern Medicine and Northwestern University. Our work throughout the community, including director appointments, illustrate the importance we put on scientific collaboration.

Research Cores

Core facilities provide cost-efficient access of state-of-the-art equipment, the most current technologies and expert technical advice to individual scientists.

Learn more about our affiliated cores

Access Research Resources

Recent Publications

Life-course socioeconomic position and the gut microbiome in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).

Batalha MA, LeCroy MN, Lin J, Peters BA, Qi Q, Wang Z, Wang T, Gallo LC, Talavera GA, McClain AC, Thyagarajan B, Daviglus ML, Hou L, Llabre M, Cai J, Kaplan RC, Isasi CR.

Gut Microbes. 2025 Dec;17(1):2479772. doi: 10.1080/19490976.2025.2479772. Epub 2025 Mar 18.

Efficacy of benznidazole delivery during Chagas disease nanotherapy is dependent on the nanocarrier morphology.

Scariot DB, Staneviciute A, Machado RRB, Yuk SA, Liu YG, Sharma S, Almunif S, Arona Mbaye EH, Nakamura CV, Engman DM, Scott EA.

Biomaterials. 2025 Nov;322:123358. doi: 10.1016/j.biomaterials.2025.123358. Epub 2025 Apr 22.

UTERINE FIBROIDS.

Bulun SE, Yin P, Wei J, Zuberi A, Iizuka T, Suzuki T, Saini P, Goad J, Parker JB, Adli M, Boyer T, Chakravarti D, Rajkovic A.

Physiol Rev. 2025 Oct 1;105(4):1947-1988. doi: 10.1152/physrev.00010.2024. Epub 2025 Apr 11.

Therapeutic targeting of circTNK2 with nanoparticles restores tamoxifen sensitivity and enhances NK cell-mediated immunity in ER-positive breast cancer.

Wu R, Yu S, Bi A, Li Y, Tiek D, Yu K, Xiong H, Shi Q, Mo Z, Yu X, Song X, Yin F, Wang Y, Yi W, Liu M, Li P, Hu B, Le A, Cheng SY, Zhou B.

Cancer Lett. 2025 Sep 1;627:217823. doi: 10.1016/j.canlet.2025.217823. Epub 2025 May 24.

Wireless, battery-free, remote photoactivation of caged-morphine for photopharmacological pain modulation without side effects.

Kim M, López-Cano M, Zhang K, Wang Y, Gómez-Santacana X, Flores Á, Wu M, Li S, Zhang H, Wei Y, Li X, Good CH, Banks AR, Llebaria A, Hernando J, Sunwoo SH, Gu J, Huang Y, Ciruela F, Rogers JA.

Biosens Bioelectron. 2025 Aug 1;281:117440. doi: 10.1016/j.bios.2025.117440. Epub 2025 Apr 4.

TRPM4 channels contribute to Adriamycin chemoresistance in breast cancer cells.

Guo J, Liu F, Yang X, Wang M, Yang S, Lan K, Yan L, Cao R, Chen X, Zhong W.

Eur J Pharmacol. 2025 Jul 5;998:177637. doi: 10.1016/j.ejphar.2025.177637. Epub 2025 Apr 16.

Spectrum of Renal Angiomyolipoma with Radiologic-Pathologic Correlation.

Lubner MG, Marko J, Taffel MT, Horowitz JM, Udager AM.

Radiographics. 2025 Jul;45(7):e240159. doi: 10.1148/rg.240159.

Unilateral pubic hair growth: a paracrine finding indicative of underlying leydig cell tumor in a prepubertal boy.

van de Walle G, Morgantini LA, Long BG, Arva NC, Hentea C, Boucher Berry CC, Osta A, Johnson EK.

Urol Case Rep. 2025 May 17;61:103071. doi: 10.1016/j.eucr.2025.103071. eCollection 2025 Jul.

Etrasimod as a treatment for eosinophilic oesophagitis (VOYAGE): a double-blind, placebo-controlled, randomised, phase 2 trial.

Dellon ES, Collins MH, Bredenoord AJ, Philpott H, Biedermann L, Dulcine M, Nguyen-Cleary T, Su C, Yu J, Tan H, Cataldi F, Wu J, Wang W, Clax P, Woolcott JC, Hirano I.

Lancet Gastroenterol Hepatol. 2025 Jul;10(7):622-633. doi: 10.1016/S2468-1253(25)00062-7. Epub 2025 May 14.

Clinicopathologic Characteristics and Prognostic Profile of Chronic Myeloid Neoplasms With Somatic NF1 Mutations in Adult Patients.

Tariq H, Loxas M, Alikhan MB, Gao J, Lu X, Chen QC, Chen YH, Altman JK, Jennings LJ, Sukhanova M.

Eur J Haematol. 2025 Jul;115(1):46-56. doi: 10.1111/ejh.14419. Epub 2025 Mar 28.

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